CHGA polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
CHGA polyclonal antibody (Cat # PAB7042) (0.1 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CHGA.
Immunogen
A synthetic peptide corresponding to human CHGA.
Sequence
C-QGAKERAHQQKKH
Host
Goat
Theoretical MW (kDa)
50.7
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CHGA polyclonal antibody (Cat # PAB7042) (0.1 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CHGA
Entrez GeneID
1113Protein Accession#
NP_001266.1Gene Name
CHGA
Gene Alias
CGA
Gene Description
chromogranin A (parathyroid secretory protein 1)
Omim ID
118910Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq
Other Designations
betagranin (N-terminal fragment of chromogranin A)|chromogranin A|parathyroid secretory protein 1
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Interactome
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Disease
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Publication Reference
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Treatment of pancreatic carcinoma by adenoviral mediated gene transfer of vasostatin in mice.
Li L, Yuan YZ, Lu J, Xia L, Zhu Y, Zhang YP, Qiao MM.
Gut 2006 Feb; 55(2):259.
Application：WB-Tr, Human, PaTu8988, SW1990 cells, Brain.
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Treatment of pancreatic carcinoma by adenoviral mediated gene transfer of vasostatin in mice.
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