SLC24A5 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SLC24A5.
Immunogen
A synthetic peptide corresponding to human SLC24A5.
Sequence
TTPDCRKKFWKN
Host
Goat
Theoretical MW (kDa)
54.9
Reactivity
Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
SLC24A5 polyclonal antibody (Cat # PAB7036) (2 ug/mL) staining of mouse eye lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SLC24A5
Entrez GeneID
283652Protein Accession#
NP_995322.1Gene Name
SLC24A5
Gene Alias
JSX, NCKX5, SHEP4
Gene Description
solute carrier family 24, member 5
Omim ID
609802Gene Ontology
HyperlinkGene Summary
This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation. [provided by RefSeq
Other Designations
ion transporter JSX|solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
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Disease
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Publication Reference
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SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans.
Lamason RL, Mohideen MA, Mest JR, Wong AC, Norton HL, Aros MC, Jurynec MJ, Mao X, Humphreville VR, Humbert JE, Sinha S, Moore JL, Jagadeeswaran P, Zhao W, Ning G, Makalowska I, McKeigue PM, O'donnell D, Kittles R, Parra EJ, Mangini NJ, Grunwald DJ, Shriver MD, Canfield VA, Cheng KC.
Science 2005 Dec; 310(5755):1782.
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SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans.
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