CNBP polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CNBP.
Immunogen
A synthetic peptide corresponding to human CNBP.
Sequence
GESGHLARECTIE
Host
Goat
Theoretical MW (kDa)
19.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CNBP polyclonal antibody (Cat # PAB7015) (2 ug/mL) staining of human muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CNBP
Entrez GeneID
7555Protein Accession#
NP_003409.1Gene Name
CNBP
Gene Alias
CNBP1, DM2, FLJ11631, PROMM, RNF163, ZCCHC22, ZNF9
Gene Description
CCHC-type zinc finger, nucleic acid binding protein
Gene Ontology
HyperlinkGene Summary
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
cellular nucleic acid binding protein|erythroid differentiation-related|myotonic dystrophy type 2 protein|sterol regulatory element-binding protein|zinc finger protein 273|zinc finger protein 9|zinc finger protein 9 (a cellular retroviral nucleic acid bin
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Interactome
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Disease
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Publication Reference
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Myotonic dystrophy type 2: molecular, diagnostic and clinical spectrum.
Day JW, Ricker K, Jacobsen JF, Rasmussen LJ, Dick KA, Kress W, Schneider C, Koch MC, Beilman GJ, Harrison AR, Dalton JC, Ranum LP.
Neurology 2003 Feb; 60(4):657.
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Myotonic dystrophy type 2: molecular, diagnostic and clinical spectrum.
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