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SPEN polyclonal antibody

  • Catalog # : PAB6987
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of SPEN.
  • Immunogen:
  • A synthetic peptide corresponding to human SPEN.
  • Sequence:
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 402
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:4000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Application Image
  • Gene Information
  • Gene Name:
  • SPEN
  • Gene Alias:
  • KIAA0929,MINT,RP1-134O19.1,SHARP
  • Gene Description:
  • spen homolog, transcriptional regulator (Drosophila)
  • Gene Summary:
  • This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq
  • Other Designations:
  • Msx2 interacting nuclear target (MINT) homolog,OTTHUMP00000010982,OTTHUMP00000044600,SMART/HDAC1 associated repressor protein,nuclear receptor transcription cofactor,spen homolog, transcriptional regulator
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