SNX9 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SNX9.
Immunogen
A synthetic peptide corresponding to internal region of human SNX9.
Sequence
C-HKGAIEKVKESDK
Host
Goat
Reactivity
Human
Form
Liquid
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
0.5 mg/mL
Recommend Usage
Peptide ELISA (antibody detection limit dilution 1:4000)
Immunofluorescence (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SNX9
Entrez GeneID
51429Protein Accession#
NP_057308.1Gene Name
SNX9
Gene Alias
MST155, MSTP155, SDP1, SH3PX1, SH3PXD3A, WISP
Gene Description
sorting nexin 9
Omim ID
605952Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein. [provided by RefSeq
Other Designations
OTTHUMP00000040083|SH3 and PX domain-containing protein SH3PX1|Wiskott-Aldrich syndrome protein (WASP) interactor protein
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Interactome
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Disease
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Publication Reference
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SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.
Soulet F, Yarar D, Leonard M, Schmid SL.
Molecular Biology of the Cell 2005 Apr; 16(4):2058.
Application：IF, Human, HeLa cells.
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SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.
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