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Last updated: 2016/12/4
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GLI2 polyclonal antibody

  • Catalog # : PAB6976
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of GLI2.
  • Immunogen:
  • A synthetic peptide corresponding to human GLI2.
  • Sequence:
  • DLKEDLDRDDCKQE
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 168
  • Specificity:
  • This antibody is expected to recognize all four reported isoforms (NP_084655.1, NP_084656.1, NP_084657.1 and NP_005261.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2736
  • Gene Name:
  • GLI2
  • Gene Alias:
  • HPE9,THP1,THP2
  • Gene Description:
  • GLI-Kruppel family member GLI2
  • Gene Summary:
  • This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq
  • Other Designations:
  • oncogene GLI2,tax helper protein 1,tax helper protein 2,tax-responsive element-2 holding protein,tax-responsive element-25-bp sequence binding protein,zinc finger protein GLI2
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