EIF2C1 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
HEK293 overexpressing EIF2C1 and probed with EIF2C1 polyclonal antibody (Cat # PAB6972) (non-transfected HEK293 in lane 2) .
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of EIF2C1.
Immunogen
A synthetic peptide corresponding to human EIF2C1.
Sequence
C-KNASYNLDPYIQEF
Host
Goat
Theoretical MW (kDa)
97.2
Reactivity
Human
Specificity
This antibody is not expected to cross-react with EIF2C2, EIF2C3 and EIF2C4.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
HEK293 overexpressing EIF2C1 and probed with EIF2C1 polyclonal antibody (Cat # PAB6972) (non-transfected HEK293 in lane 2) .Enzyme-linked Immunoabsorbent Assay
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Gene Info — EIF2C1
Entrez GeneID
26523Protein Accession#
NP_0.36331.1Gene Name
EIF2C1
Gene Alias
AGO1, DKFZp686M13167, EIF2C, GERP95, Q99
Gene Description
eukaryotic translation initiation factor 2C, 1
Omim ID
606228Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and argonaute 4. [provided by RefSeq
Other Designations
Golgi Endoplasmic Reticulum protein 95 kDa|OTTHUMP00000008519|argonaute 1|putative RNA-binding protein Q99
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Interactome
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Disease
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Publication Reference
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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing.
Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R.
Cell 2005 Nov; 123(4):631.
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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing.
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