ERG polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ERG.
Immunogen
A synthetic peptide corresponding to C-terminus of human ERG.
Sequence
C-PNTRLPTSHMPSH
Host
Goat
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ERG polyclonal antibody (Cat # PAB6943) (10 ug/mL) staining of paraffin embedded human prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ERG
Entrez GeneID
2078Protein Accession#
NP_891548.1;NP_004440.1;NP_001129626.1;NP_001129627.1Gene Name
ERG
Gene Alias
erg-3, p55
Gene Description
v-ets erythroblastosis virus E26 oncogene homolog (avian)
Omim ID
165080Gene Ontology
HyperlinkOther Designations
OTTHUMP00000115970|TMPRSS2-ERG prostate cancer specific|transcriptional regulator ERG (transforming protein ERG)|v-ets avian erythroblastosis virus E26 oncogene related|v-ets erythroblastosis virus E26 oncogene like
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Interactome
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Disease
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Publication Reference
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Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, Pienta KJ, Rubin MA, Chinnaiyan AM.
Science 2005 Oct; 310(5748):644.
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Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
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