DCDC2 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
DCDC2 polyclonal antibody (Cat # PAB6931) (0.2 ug/mL) staining of COS-7 cell lysate transfected with full length recombinant human DCDC2 (A) and untransfected control COS-7 cells (B). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of DCDC2.
Immunogen
A synthetic peptide corresponding to internal region of human DCDC2.
Sequence
C-DGEKANKDAEQKED
Host
Goat
Theoretical MW (kDa)
52.8
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:4000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
DCDC2 polyclonal antibody (Cat # PAB6931) (0.2 ug/mL) staining of COS-7 cell lysate transfected with full length recombinant human DCDC2 (A) and untransfected control COS-7 cells (B). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — DCDC2
Entrez GeneID
51473Protein Accession#
NP_057440.2Gene Name
DCDC2
Gene Alias
DCDC2A, RU2, RU2S
Gene Description
doublecortin domain containing 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with two doublecortin peptide domains. This domain has been demonstrated to bind tubulin and enhance microtubule polymerization. Mutations in this gene have been associated with Reading Disability (RD), also referred to as developmental dyslexia. [provided by RefSeq
Other Designations
OTTHUMP00000017887
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Interactome
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Disease
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Publication Reference
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Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia.
Cope N, Harold D, Hill G, Moskvina V, Stevenson J, Holmans P, Owen MJ, O'Donovan MC, Williams J.
American Journal of Human Genetics 2005 Apr; 76(4):581.
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Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia.
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