SLITRK1 polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of SLITRK1.
Immunogen
A synthetic peptide corresponding to human SLITRK1.
Sequence
NADGAHRVYDCGSHS
Host
Goat
Theoretical MW (kDa)
77.7
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SLITRK1
Entrez GeneID
114798Protein Accession#
NP_443142Gene Name
SLITRK1
Gene Alias
FLJ54428, KIAA0918, KIAA1910, LRRC12, RP11-395N17.1
Gene Description
SLIT and NTRK-like family, member 1
Gene Ontology
HyperlinkGene Summary
Members of the SLITRK family, such as SLITRK1, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, but not SLITRK1, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM
Other Designations
OTTHUMP00000018546|leucine rich repeat containing 12|slit and trk like 1 protein|slit and trk like gene 1
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Interactomes
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Diseases
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Publication Reference
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Sequence variants in SLITRK1 are associated with Tourette's syndrome.
Abelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LS 4th, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, State MW.
Science 2005 Oct; 310(5746):317.
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Sequence variants in SLITRK1 are associated with Tourette's syndrome.
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