DCLRE1A polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of DCLRE1A.
Immunogen
A synthetic peptide corresponding to human DCLRE1A.
Sequence
PSPNQKRSSQCKRK
Host
Goat
Theoretical MW (kDa)
117
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — DCLRE1A
Entrez GeneID
9937Protein Accession#
NP_055696.2Gene Name
DCLRE1A
Gene Alias
KIAA0086, PSO2, SNM1, SNM1A, hSNM1
Gene Description
DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae)
Omim ID
609682Gene Ontology
HyperlinkGene Summary
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1A is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM
Other Designations
DNA-crosslink repair gene SNM1|OTTHUMP00000020516|OTTHUMP00000020517
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Interactome
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Disease
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Publication Reference
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Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress.
Akhter S, Richie CT, Deng JM, Brey E, Zhang X, Patrick C Jr, Behringer RR, Legerski RJ.
Molecular and Cellular Biology 2004 Dec; 24(23):10448.
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Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress.
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