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Last updated: 2017/4/23
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NOTCH3 polyclonal antibody

  • Catalog # : PAB6918
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of NOTCH3.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human NOTCH3.
  • Sequence:
  • C-QLGPQPEVTPKRQ
  • Host:
  • Goat
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • NOTCH3 polyclonal antibody (4 ug/mL) staining of paraffin embedded human hippocampus. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4854
  • Gene Name:
  • NOTCH3
  • Gene Alias:
  • CADASIL,CASIL
  • Gene Description:
  • Notch homolog 3 (Drosophila)
  • Gene Summary:
  • This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq
  • Other Designations:
  • Notch homolog 3
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