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Last updated: 2016/12/4
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KL polyclonal antibody

  • Catalog # : PAB6906
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of KL.
  • Immunogen:
  • A synthetic peptide corresponding to human KL.
  • Sequence:
  • C-KRDDAKYMYYLKK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 116, 62.1
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_004786.2, NP_710150.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:4000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • Suppression of aging in mice by the hormone Klotho.
    Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M.Science. 2005 Sep 16;309(5742):1829-33. Epub 2005 Aug 25.
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9365
  • Protein Accession#:
  • NP_004786.2;NP_710150.1
  • Gene Name:
  • KL
  • Gene Alias:
  • -
  • Gene Description:
  • klotho
  • Gene Summary:
  • This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018796
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