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Last updated: 2016/12/11
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UCP1 polyclonal antibody

  • Catalog # : PAB6905
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of UCP1.
  • Immunogen:
  • A synthetic peptide corresponding to human UCP1.
  • Sequence:
  • C-EQLKRELSKSRQ
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 33
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.1-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • UCP1 polyclonal antibody (Cat # PAB6905) (1 ug/mL) staining of human adipose lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7350
  • Gene Name:
  • UCP1
  • Gene Alias:
  • SLC25A7,UCP
  • Gene Description:
  • uncoupling protein 1 (mitochondrial, proton carrier)
  • Gene Summary:
  • Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq
  • Other Designations:
  • mitochondrial brown fat uncoupling protein,thermogenin,uncoupling protein 1
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