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Last updated: 2017/7/23
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TIRAP polyclonal antibody

  • Catalog # : PAB6892
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TIRAP.
  • Immunogen:
  • A synthetic peptide corresponding to human TIRAP.
  • Sequence:
  • C-QTLLKKPKKRPNSPE
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 23.9, 24.8
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_001034750.1 and NP_683708.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • TIRAP polyclonal antibody (Cat # PAB6892) (0.1 ug/mL) staining of K-562 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_001034750.1;NP_683708.1
  • Gene Name:
  • TIRAP
  • Gene Alias:
  • FLJ42305,Mal,wyatt
  • Gene Description:
  • toll-interleukin 1 receptor (TIR) domain containing adaptor protein
  • Gene Summary:
  • The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq
  • Other Designations:
  • MyD88 adapter-like protein,OTTHUMP00000179130,OTTHUMP00000179132,TIR domain-containing adapter protein,TIR domain-containing adaptor protein,Toll-interleukin 1 receptor (TIR) domain-containing adapter protein,Toll-interleukin 1 receptor (TIR) domain-conta
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