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Last updated: 2016/12/4
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CFL2 polyclonal antibody

  • Catalog # : PAB6848
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CFL2.
  • Immunogen:
  • A synthetic peptide corresponding to human CFL2.
  • Sequence:
  • C-DIKDRSTLGEK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 18.7, 18.7
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_068733 and NP_619579).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.01-0.03 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CFL2 polyclonal antibody (Cat # PAB6848) (0.003 ug/mL) staining of human muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1073
  • Protein Accession#:
  • NP_068733.1;NP_619579.1
  • Gene Name:
  • CFL2
  • Gene Alias:
  • NEM7
  • Gene Description:
  • cofilin 2 (muscle)
  • Gene Summary:
  • This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • cofilin 2
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