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Last updated: 2017/12/17
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STX1A/STX1B2 polyclonal antibody

  • Catalog # : PAB6845
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of STX1A/STX1B2.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human STX1A, STX1B2.
  • Sequence:
  • KDRTQELRTAKD-C
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 33.0, 33.2
  • Reactivity:
  • Mouse
  • Specificity:
  • This product is expected to recognize the products of 2 different genes. STX1A (NP_004594.1and NP_001159375.1) and STX1B (NP_443106.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.01-0.03 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • The STX1A/STX1B2 polyclonal antibody (Cat # PAB6845) (0.003 ug/mL) staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6804
  • Protein Accession#:
  • NP_004594.1 (Gene ID : 6804);NP_001159375.1 (Gene ID : 112755);NP_443106.1 (Gene ID : 112755)
  • Gene Name:
  • STX1A
  • Gene Alias:
  • HPC-1,STX1,p35-1
  • Gene Description:
  • syntaxin 1A (brain)
  • Gene Summary:
  • Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM
  • Other Designations:
  • -
  • Gene Information
  • Protein Accession#:
  • NP_004594.1 (Gene ID : 6804);NP_001159375.1 (Gene ID : 112755);NP_443106.1 (Gene ID : 112755)
  • Gene Name:
  • STX1B
  • Gene Alias:
  • STX1B1,STX1B2
  • Gene Description:
  • syntaxin 1B
  • Other Designations:
  • syntaxin 1B1,syntaxin 1B2
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