MEFV polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MEFV.
Immunogen
A synthetic peptide corresponding to human MEFV.
Sequence
C-EHLKKLRKSGEEQ
Host
Goat
Theoretical MW (kDa)
86.4
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — MEFV
Entrez GeneID
4210Protein Accession#
NP_000234.1Gene Name
MEFV
Gene Alias
FMF, MEF, MGC126560, MGC126586, TRIM20
Gene Description
Mediterranean fever
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. [provided by RefSeq
Other Designations
Mediterranean fever protein|OTTHUMP00000159670|marenostrin|pyrin
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Interactome
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Disease
- Abdomen
- Abdominal Pain
- Acute Disease
- Albuminuria
- Alzheimer disease
- Amyloidosis
- Arthritis
- Asthma
- Atherosclerosis
+ View More Disease
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Publication Reference
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Severe disease in patients with rheumatoid arthritis carrying a mutation in the Mediterranean fever gene.
Rabinovich E, Livneh A, Langevitz P, Brezniak N, Shinar E, Pras M, Shinar Y.
Annals of the Rheumatic Diseases 2005 Jul; 64(7):1009.
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Severe disease in patients with rheumatoid arthritis carrying a mutation in the Mediterranean fever gene.
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