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Last updated: 2016/10/23
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GHRL polyclonal antibody

  • Catalog # : PAB6842
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of GHRL.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human GHRL.
  • Sequence:
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 12.9
  • Reactivity:
  • Human, Rat
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • GHRL polyclonal antibody (Cat # PAB6842) (2 ug/mL) staining of paraffin embedded human placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • Immunocytochemistry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunocytochemistry
  • Gene Information
  • Protein Accession#:
  • NP_057446.1;NP_001128413.1;NP_001128416.1;NP_001128417.1;NP_001128418.1
  • Gene Name:
  • GHRL
  • Gene Alias:
  • MTLRP,obestatin
  • Gene Description:
  • ghrelin/obestatin prepropeptide
  • Gene Summary:
  • This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq
  • Other Designations:
  • ghrelin, growth hormone secretagogue receptor ligand,ghrelin/obestatin,ghrelin/obestatin preprohormone,motilin-related peptide
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