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Last updated: 2017/1/22
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HMGA1 polyclonal antibody

  • Catalog # : PAB6836
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of HMGA1.
  • Immunogen:
  • A synthetic peptide corresponding to human HMGA1.
  • Sequence:
  • C-LASKQEKDGTEK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 11.7, 10.7
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoform a (also called HMG-I, NP_665906.1, NP_665908.1, NP_665911.1) and isoform b (also called HMG-Y, NP_002122.1, NP_665909.1, NP_665910.1, NP_665912.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • HMGA1 polyclonal antibody (Cat # PAB6836) (4 ug/mL) staining of paraffin embedded human placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3159
  • Protein Accession#:
  • NP_665906.1;NP_665908.1;NP_665911.1;NP_002122.1;NP_665909.1;NP_665912.1;NP_665910.1
  • Gene Name:
  • HMGA1
  • Gene Alias:
  • HMG-R,HMGA1A,HMGIY,MGC12816,MGC4242,MGC4854
  • Gene Description:
  • high mobility group AT-hook 1
  • Gene Summary:
  • This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000016222,OTTHUMP00000016223,OTTHUMP00000016224,OTTHUMP00000039618,high-mobility group (nonhistone chromosomal) protein isoforms I and Y,nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y
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