Products

Western Blot (Cell lysate)

KLRK1 polyclonal antibody (Cat # PAB6828) staining (0.5 ug/mL) of MOLT-4 cell lysate (1) + peptide (2). (35 ug protein in RIPA buffer). Detected by chemiluminescence.

Enzyme-linked Immunoabsorbent Assay

Flow Cytometry

KLRK1 polyclonal antibody (Cat # PAB6828) Flow cytometric analysis of human peripheral blood monocytes. Primary incubation 30 minutes (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL).

Entrez GeneID

22914

Protein Accession#

NP_0.31386.1

Gene Name

KLRK1

Gene Alias

CD314, D12S2489E, FLJ17759, FLJ75772, KLR, NKG2-D, NKG2D

Gene Description

killer cell lectin-like receptor subfamily K, member 1

Gene Ontology

Hyperlink

Gene Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. [provided by RefSeq

Other Designations

NK cell receptor D|NKG2-D type II integral membrane protein