GPX2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GPX2.
Immunogen
A synthetic peptide corresponding to human GPX2.
Sequence
C-SLDGEKVDFN
Host
Goat
Theoretical MW (kDa)
21.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
GPX2 polyclonal antibody (Cat # PAB6817) staining (1 ug/mL) of human prostate lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — GPX2
Entrez GeneID
2877Protein Accession#
NP_002074.2Gene Name
GPX2
Gene Alias
GI-GPx, GPRP, GSHPX-GI, GSHPx-2
Gene Description
glutathione peroxidase 2 (gastrointestinal)
Omim ID
138319Gene Ontology
HyperlinkGene Summary
This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract. [provided by RefSeq
Other Designations
gastrointestinal glutathione peroxidase 2|glutathione peroxidase 2|glutathione peroxidase-related protein 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia.
McGrath-Morrow S, Lauer T, Yee M, Neptune E, Podowski M, Thimmulappa RK, O'Reilly M, Biswal S.
American Journal of Physiology. Lung Cellular and Molecular Physiology 2009 Jan; 296(4):L565.
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Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia.
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