DPP10 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
DPP10 polyclonal antibody (Cat # PAB6788) (0.1 ug/mL) staining of human bone marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of DPP10.
Immunogen
A synthetic peptide corresponding to human DPP10.
Sequence
C-DEGHNVSEKSKYHL
Host
Goat
Theoretical MW (kDa)
90.9, 90.1
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms NP_065919 and NP_001004360.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
DPP10 polyclonal antibody (Cat # PAB6788) (0.1 ug/mL) staining of human bone marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — DPP10
Entrez GeneID
57628Protein Accession#
NP_065919.2;NP_001004360.1Gene Name
DPP10
Gene Alias
DPL2, DPPY, DPRP3
Gene Description
dipeptidyl-peptidase 10
Omim ID
608209Gene Ontology
HyperlinkGene Summary
This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
dipeptidyl peptidase 10|dipeptidyl peptidase IV-related protein 3|dipeptidyl peptidase X|dipeptidyl peptidase like protein 2
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Interactome
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Disease
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Publication Reference
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A review of asthma genetics: gene expression studies and recent candidates.
Malerba G, Pignatti PF.
J Appl Genet 2005 Jan; 46(1):93.
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A review of asthma genetics: gene expression studies and recent candidates.
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