RICTOR polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
RICTOR polyclonal antibody (Cat # PAB6780) (2.5 ug/mL) staining of paraffin embedded human kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of RICTOR.
Immunogen
A synthetic peptide corresponding to human RICTOR.
Sequence
C-KQPIVDTSAES
Host
Goat
Theoretical MW (kDa)
192
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
Immunohistochemistry (2-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
RICTOR polyclonal antibody (Cat # PAB6780) (2.5 ug/mL) staining of paraffin embedded human kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — RICTOR
Entrez GeneID
253260Protein Accession#
NP_689969.2Gene Name
RICTOR
Gene Alias
DKFZp686B11164, KIAA1999, MGC39830, mAVO3
Gene Description
rapamycin-insensitive companion of mTOR
Omim ID
609022Gene Ontology
HyperlinkGene Summary
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM
Other Designations
TORC2-specific protein AVO3|pianissimo
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Interactome
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Pathway
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Disease
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Publication Reference
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An Immunohistochemical Study of the PTEN/AKT Pathway Involvement in Canine and Feline Mammary Tumors.
Pietro Asproni, Francesca Millanta, Lorenzo Ressel, Fabio Podestà, Francesca Parisi, Iacopo Vannozzi, Alessandro Poli.
Animals 2021 Feb; 11(2):365.
Application：IHC-P, Cat, Dog, Dog mammary carcinomas, Feline mammary carcinomas.
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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM.
Current Biology 2004 Jul; 14(14):1296.
Application：IP, WB, Human, DU145, HEK 293T, HeLa cells.
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An Immunohistochemical Study of the PTEN/AKT Pathway Involvement in Canine and Feline Mammary Tumors.
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