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Last updated: 2016/11/27
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GAD2 polyclonal antibody

  • Catalog # : PAB6778
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of GAD2.
  • Immunogen:
  • A synthetic peptide corresponding to human GAD2.
  • Sequence:
  • C-TLEDNEERMSRLSK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 65.4, 65.4
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • GAD2 polyclonal antibody (Cat # PAB6778) (0.1 ug/mL) staining of human brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2572
  • Gene Name:
  • GAD2
  • Gene Alias:
  • GAD65,MGC161605,MGC161607
  • Gene Description:
  • glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • Gene Summary:
  • This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq
  • Other Designations:
  • Glutamate decarboxylase-2 (pancreas),OTTHUMP00000019335,OTTHUMP00000019336,glutamate decarboxylase 2,glutamate decarboxylase 2 (pancreatic islets and brain, 65kD)
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