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Last updated: 2017/3/26
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PCSK9 polyclonal antibody

  • Catalog # : PAB6761
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PCSK9.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human PCSK9.
  • Sequence:
  • CRSRHLAQASQELQ
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 74.3
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.3 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-6 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • PCSK9 polyclonal antibody (Cat # PAB6761) staining (0.2 ug/mL) of McA cell lysates: untransfected (Lane 1), transfected with wild type human PCSK9 (Lane 2), transfected with S127R human PCSK9 (Lane 3).
    Data kindly provided by Dr. X-M Sun, Hammersmith Hospital, London.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • PCSK9 polyclonal antibody (Cat # PAB6761) (4 ug/mL) staining of paraffin embedded human kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • PCSK9
  • Gene Alias:
  • FH3,HCHOLA3,LDLCQ1,NARC-1,NARC1
  • Gene Description:
  • proprotein convertase subtilisin/kexin type 9
  • Gene Summary:
  • This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000009833,convertase subtilisin/kexin type 9 preproprotein,neural apoptosis regulated convertase 1
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