MOG polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
MOG polyclonal antibody (Cat # PAB6753) staining (0.03 ug/mL) of human brain lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MOG.
Immunogen
A synthetic peptide corresponding to human MOG.
Sequence
C-AGQFLEELRNPF
Host
Goat
Theoretical MW (kDa)
28.2, 23.6, 25.4
Reactivity
Human
Specificity
This antibody is expected to recognize NP_002424 (isf 1), NP_996532 (isf a1), NP_001008229 (isf a3), NP_996535 (isf a2)
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.03-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
MOG polyclonal antibody (Cat # PAB6753) staining (0.03 ug/mL) of human brain lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MOG
Entrez GeneID
4340Protein Accession#
NP_002424;NP_996532;NP_001008229;NP_996535Gene Name
MOG
Gene Alias
MGC26137, MOGIG-2
Gene Description
myelin oligodendrocyte glycoprotein
Omim ID
159465Gene Ontology
HyperlinkGene Summary
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
MOG Ig-AluB|MOG alpha-6|OTTHUMP00000029122|OTTHUMP00000029124|OTTHUMP00000029125|OTTHUMP00000029126|OTTHUMP00000029127
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Interactome
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Disease
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Publication Reference
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Neuroprotective Effects of Recombinant T-cell Receptor Ligand in Autoimmune Optic Neuritis in HLA-DR2 Mice.
Adamus G, Brown L, Andrew S, Meza-Romero R, Burrows GG, Vandenbark AA.
Investigative Ophthalmology & Visual Science 2012 Jan; 53(1):406.
Application：IF, Mouse, Oligodendrocyte.
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Genetic study of the myelin oligodendrocyte glycoprotein (MOG) gene in schizophrenia.
Zai G, King N, Wigg K, Couto J, Wong GW, Honer WG, Barr CL, Kennedy JL.
Genes, Brain, and Behavior 2005 Feb; 4(1):2.
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Neuroprotective Effects of Recombinant T-cell Receptor Ligand in Autoimmune Optic Neuritis in HLA-DR2 Mice.
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