DYX1C1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of DYX1C1.
Immunogen
A synthetic peptide corresponding to human DYX1C1.
Sequence
C-KIRNVIQGTELKS
Host
Goat
Theoretical MW (kDa)
48.5
Reactivity
Human
Specificity
This antibody is expected to recognize only one of the three reported isoforms (NP_570722.2, isoform a).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Immunohistochemistry (5-10 ug/mL)
Western Blot (0.1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
DYX1C1 polyclonal antibody (Cat # PAB6746) staining (0.1 ug/mL) of COS-1 cell lysates: untransfected (right lane) and transfected with full length recombinant human DYX1C1 (left lane). Data kindly provided by Wang and LoTurco, University of Connecticut, USA.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
DYX1C1 polyclonal antibody (Cat # PAB6746) (5 ug/mL) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — DYX1C1
Entrez GeneID
161582Protein Accession#
NP_570722.2Gene Name
DYX1C1
Gene Alias
DYX1, DYXC1, EKN1, FLJ37882, MGC70618, RD
Gene Description
dyslexia susceptibility 1 candidate 1
Gene Ontology
HyperlinkOther Designations
OTTHUMP00000162853
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Interactome
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Disease
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Publication Reference
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DYX1C1 functions in neuronal migration in developing neocortex.
Wang Y, Paramasivam M, Thomas A, Bai J, Kaminen-Ahola N, Kere J, Voskuil J, Rosen GD, Galaburda AM, Loturco JJ.
Neuroscience 2006 Sep; 143(2):515.
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DYX1C1 functions in neuronal migration in developing neocortex.
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