SRD5A1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SRD5A1.
Immunogen
A synthetic peptide corresponding to human SRD5A1.
Sequence
ATATGVAEERLLC
Host
Goat
Theoretical MW (kDa)
29.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SRD5A1
Entrez GeneID
6715Protein Accession#
NP_001038.1Gene Name
SRD5A1
Gene Alias
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Gene Description
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Omim ID
184753Gene Ontology
HyperlinkGene Summary
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM
Other Designations
3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1|5-alpha reductase|OTTHUMP00000115519|steroid 5-alpha-reductase type I|steroid-5-alpha-reductase 1
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Interactome
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Pathway
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Disease
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Publication Reference
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The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate.
Iczkowski KA, Qiu J, Qian J, Somerville MC, Rittmaster RS, Andriole GL, Bostwick DG.
Urology 2005 Jan; 65(1):76.
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The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate.
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