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Last updated: 2017/11/12
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ADH1A/ADH1B/ADH1C polyclonal antibody

  • Catalog # : PAB6725
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of ADH1A/ADH1B/ADH1C.
  • Immunogen:
  • A synthetic peptide corresponding to human ADH1A/ADH1B/ADH1C.
  • Sequence:
  • STAGKVMKCKA
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 39.9
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize the alpha (ADH1A, NP_ 000658), the beta (ADH1B, NP_000659) and gamma (ADH1C, NP_000660) polyvariants of human alcohol dehydrogenase.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.3-1.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • The ADH1A/ADH1B/ADH1C polyclonal antibody (Cat # PAB6725) (0.3 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Immunohistochemistry
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 124
  • Protein Accession#:
  • NP_000658.1 (Gene ID : 124);NP_000659.2 (Gene ID : 125);NP_000660.1 (Gene ID : 126)
  • Gene Name:
  • ADH1A
  • Gene Alias:
  • ADH1
  • Gene Description:
  • alcohol dehydrogenase 1A (class I), alpha polypeptide
  • Gene Summary:
  • This gene encodes class I alcohol dehydrogenase, alpha subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. This gene is monomorphic and predominant in fetal and infant livers, whereas the genes encoding beta and gamma subunits are polymorphic and strongly expressed in adult livers. [provided by RefSeq
  • Other Designations:
  • ADH, alpha subunit,alcohol dehydrogenase 1 (class I), alpha polypeptide,aldehyde reductase,class I alcohol dehydrogenase, alpha subunit
  • Gene Information
  • Entrez GeneID:
  • 125
  • Protein Accession#:
  • NP_000658.1 (Gene ID : 124);NP_000659.2 (Gene ID : 125);NP_000660.1 (Gene ID : 126)
  • Gene Name:
  • ADH1B
  • Gene Alias:
  • ADH2,DKFZp686C06125
  • Gene Description:
  • alcohol dehydrogenase 1B (class I), beta polypeptide
  • Gene Summary:
  • The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq
  • Other Designations:
  • ADH, beta subunit,alcohol dehydrogenase 2 (class I), beta polypeptide,alcohol dehydrogenase IB (class I), beta polypeptide,aldehyde reductase,class I alcohol dehydrogenase, beta subunit
  • Gene Information
  • Entrez GeneID:
  • 126
  • Protein Accession#:
  • NP_000658.1 (Gene ID : 124);NP_000659.2 (Gene ID : 125);NP_000660.1 (Gene ID : 126)
  • Gene Name:
  • ADH1C
  • Gene Alias:
  • ADH3
  • Gene Description:
  • alcohol dehydrogenase 1C (class I), gamma polypeptide
  • Gene Summary:
  • This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq
  • Other Designations:
  • ADH, gamma subunit,alcohol dehydrogenase 3 (class I), gamma polypeptide,aldehyde reductase,class I alcohol dehydrogenase, gamma subunit
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