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Last updated: 2017/6/25
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HSD11B1 polyclonal antibody

  • Catalog # : PAB6723
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of HSD11B1.
  • Immunogen:
  • A synthetic peptide corresponding to human HSD11B1.
  • Sequence:
  • CTSYNMDRFINK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 32.4
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize human HSD11B1 protein. Both NP_005516.1 and NP_861420.1 variants encode the same protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:4000)
    Western Blot (0.3-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • HSD11B1 polyclonal antibody (Cat # PAB6723) (0.3 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3290
  • Protein Accession#:
  • NP_005516.1;NP_861420.1
  • Gene Name:
  • HSD11B1
  • Gene Alias:
  • 11-DH,11-beta-HSD1,HDL,HSD11,HSD11B,HSD11L,MGC13539,SDR26C1
  • Gene Description:
  • hydroxysteroid (11-beta) dehydrogenase 1
  • Gene Summary:
  • The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 11-beta-hydroxysteroid dehydrogenase 1,OTTHUMP00000034649,OTTHUMP00000034650,corticosteroid 11-beta-dehydrogenase isozyme 1,short chain dehydrogenase/reductase family 26C, member 1
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