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Last updated: 2017/4/30
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ADAM12 polyclonal antibody

  • Catalog # : PAB6697
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of ADAM12.
  • Immunogen:
  • A synthetic peptide corresponding to human ADAM12.
  • Sequence:
  • AARPLPVSPARALC
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 99.6, 80.5
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both the longer membrane-bound form of human ADAM12 (NP_003465) and the shorter soluble ADAM12 splice isoform (NP_067673). This antibody does not cross-react with other ADAMS.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Western blot (0.1-0.3 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • ADAM12 polyclonal antibody (Cat # PAB6697) staining (0.1 ug/mL) of human heart lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • Immunohistochemistry
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8038
  • Protein Accession#:
  • NP_003465;NP_067673
  • Gene Name:
  • ADAM12
  • Gene Alias:
  • MCMP,MCMPMltna,MLTN,MLTNA
  • Gene Description:
  • ADAM metallopeptidase domain 12
  • Gene Summary:
  • This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020727,OTTHUMP00000046766,a disintegrin and metalloproteinase domain 12 (meltrin alpha),meltrin alpha
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