PRDM4 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PRDM4.
Immunogen
A synthetic peptide corresponding to human PRDM4.
Sequence
CSAVYSADESLSAHK
Host
Goat
Theoretical MW (kDa)
87.9
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Western Blot (0.3-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PRDM4 polyclonal antibody (Cat # PAB6695) (0.3 ug/mL) staining of human brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PRDM4
Entrez GeneID
11108Protein Accession#
NP_0.36538Gene Name
PRDM4
Gene Alias
MGC45046, PFM1
Gene Description
PR domain containing 4
Omim ID
605780Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes. [provided by RefSeq
Other Designations
PR-domain zinc-finger protein PFM1
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Interactome
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Pathway
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Disease
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Publication Reference
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The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E.
Chittka A, Arevalo JC, Rodriguez-Guzman M, Perez P, Chao MV, Sendtner M.
The Journal of Cell Biology 2004 Mar; 164(7):985.
Application:WB, Rat, PC-12 cells.
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The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E.
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