RXRA polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of RXRA.
Immunogen
A synthetic peptide corresponding to human RXRA.
Sequence
CQVNSSLTSPTGRGSM
Host
Goat
Theoretical MW (kDa)
50.8
Reactivity
Human
Specificity
This antibody is expected to recognize an epitope corresponding to human RXR alpha protein and does not cross-react with either RXR beta or gamma.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.5-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
RXRA polyclonal antibody (Cat # PAB6692) (0.5 ug/mL) staining of A-431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — RXRA
Entrez GeneID
6256Protein Accession#
NP_002948.1Gene Name
RXRA
Gene Alias
FLJ00280, FLJ00318, FLJ16020, FLJ16733, MGC102720, NR2B1
Gene Description
retinoid X receptor, alpha
Omim ID
180245Gene Ontology
HyperlinkGene Summary
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. [provided by RefSeq
Other Designations
OTTHUMP00000022510
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.
Claudel T, Leibowitz MD, Fievet C, Tailleux A, Wagner B, Repa JJ, Torpier G, Lobaccaro JM, Paterniti JR, Mangelsdorf DJ, Heyman RA, Auwerx J.
PNAS 2001 Feb; 98(5):2610.
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Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.
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