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Last updated: 2016/12/4
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NR1H2 polyclonal antibody

  • Catalog # : PAB6690
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of NR1H2.
  • Immunogen:
  • A synthetic peptide corresponding to human NR1H2.
  • Sequence:
  • SSPTTSSLDTPLPGC
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 51
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to be specific to LXR beta and not to cross-react with LXR alpha.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Western blot (1-3 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • NR1H2 polyclonal antibody (Cat # PAB6690) (1 ug/mL) staining of human bone marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • NR1H2 polyclonal antibody (Cat # PAB6690) (3 ug/mL) staining of paraffin embedded human spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7376
  • Gene Name:
  • NR1H2
  • Gene Alias:
  • LXR-b,LXRB,NER,NER-I,RIP15,UNR
  • Gene Description:
  • nuclear receptor subfamily 1, group H, member 2
  • Gene Summary:
  • The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995 [PubMed 7625741]).[supplied by OMIM
  • Other Designations:
  • LX receptor beta,liver X receptor beta,liver X receptor-beta,nuclear orphan receptor LXR-beta,oxysterols receptor LXR-beta,steroid hormone-nuclear receptor NER,ubiquitously-expressed nuclear receptor
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