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Last updated: 2017/12/10
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CASP4 polyclonal antibody

  • Catalog # : PAB6681
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CASP4.
  • Immunogen:
  • A synthetic peptide corresponding to human CASP4.
  • Sequence:
  • CKERAEEIYPIKERN
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 43.3, 36.7
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize all 3 isoforms of CASP4 (alpha, represented by NP_001216, gamma, NP-150649 and delta NP_150650).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.3-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CASP4 polyclonal antibody (Cat # PAB6681) (0.3 ug/mL) staining of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CASP4 polyclonal antibody (Cat # PAB6681) (1 ug/mL) staining of human brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 837
  • Protein Accession#:
  • NP_001216;NP_150649;NP_150650
  • Gene Name:
  • CASP4
  • Gene Alias:
  • ICE(rel)II,ICEREL-II,ICH-2,Mih1/TX,TX
  • Gene Description:
  • caspase 4, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • apoptotic cysteine protease Mih1/TX,caspase 4,caspase 4, apoptosis-related cysteine protease
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