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Last updated: 2016/10/23
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PPARD polyclonal antibody

  • Catalog # : PAB6679
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PPARD.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human PPARD.
  • Sequence:
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 49.9
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody is expected to recognize isoform 1 (NP_006229) of PPAR delta, but not isoform 2, a shorter protein (NP_80.3184) with a different C-terminus.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • PPARD polyclonal antibody (Cat # PAB6679) (0.3 ug/mL) staining of Jurkat lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5467
  • Gene Name:
  • Gene Alias:
  • Gene Description:
  • peroxisome proliferator-activated receptor delta
  • Gene Summary:
  • This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000016256,nuclear hormone receptor 1,peroxisome proliferative activated receptor, delta
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