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Last updated: 2016/12/4
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ANTXR1 polyclonal antibody

  • Catalog # : PAB6677
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of ANTXR1.
  • Immunogen:
  • A synthetic peptide corresponding to human ANTXR1.
  • Sequence:
  • C-RAPPPSRPPPRPSV
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 62.8
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize variant 1 (NP_115584) only.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (0.2-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • ANTXR1 polyclonal antibody (Cat # PAB6677) staining (0.3 ug/mL) of human PBMC lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • ANTXR1
  • Gene Alias:
  • ATR,FLJ10601,FLJ11298,FLJ21776,TEM8
  • Gene Description:
  • anthrax toxin receptor 1
  • Gene Summary:
  • This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq
  • Other Designations:
  • 2310008J16Rik,2810405N18Rik,tumor endothelial marker 8
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