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Last updated: 2016/12/4
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SH2B3 polyclonal antibody

  • Catalog # : PAB6669
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of SH2B3.
  • Immunogen:
  • A synthetic peptide corresponding to human SH2B3.
  • Sequence:
  • NGPALQPSSPC
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 63.2
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • SH2B3 polyclonal antibody (Cat # PAB6669) (0.3 ug/mL) staining of MOLT 4 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • HEK293 overexpressing SH2B3 and probed with SH2B3 polyclonal antibody (Cat # PAB6669) (mock transfection in first lane), tested by Origene.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • SH2B3
  • Gene Alias:
  • CELIAC13,LNK
  • Gene Description:
  • SH2B adaptor protein 3
  • Gene Summary:
  • T-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM
  • Other Designations:
  • lymphocyte adaptor protein
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