CD2BP2 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CD2BP2.
Immunogen
A synthetic peptide corresponding to human CD2BP2.
Sequence
PKRKVTFQGVGDE-C
Host
Goat
Theoretical MW (kDa)
37.6
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CD2BP2 polyclonal antibody (Cat # PAB6651) (0.3 ug/mL) staining of human thymus lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CD2BP2
Entrez GeneID
10421Protein Accession#
NP_006101.1Gene Name
CD2BP2
Gene Alias
FWP010, LIN1, Snu40, U5-52K
Gene Description
CD2 (cytoplasmic tail) binding protein 2
Omim ID
604470Gene Ontology
HyperlinkGene Summary
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq
Other Designations
CD2 antigen (cytoplasmic tail) binding protein 2|CD2 binding protein 2|CD2 cytoplasmic domain binding protein 2|U5 snRNP 52K protein
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Interactome
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Publication Reference
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Identification of a proline-binding motif regulating CD2-triggered T lymphocyte activation.
Nishizawa K, Freund C, Li J, Wagner G, Reinherz EL.
PNAS 1998 Dec; 95(25):14897.
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Identification of a proline-binding motif regulating CD2-triggered T lymphocyte activation.
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