MSX1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MSX1.
Immunogen
A synthetic peptide corresponding to human MSX1.
Sequence
TSLPLGVKVEDS-C
Host
Goat
Theoretical MW (kDa)
30.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Immunohistochemistry (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
MSX1 polyclonal antibody (Cat # PAB6647) (2.5 ug/mL) staining of paraffin embedded human prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MSX1
Entrez GeneID
4487Protein Accession#
NP_002439Gene Name
MSX1
Gene Alias
HOX7, HYD1
Gene Description
msh homeobox 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq
Other Designations
OTTHUMP00000115387|homeobox 7|msh homeo box 1|msh homeobox homolog 1
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Interactome
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Disease
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Publication Reference
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Endogenous Msx1 antisense transcript: in vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals.
Blin-Wakkach C, Lezot F, Ghoul-Mazgar S, Hotton D, Monteiro S, Teillaud C, Pibouin L, Orestes-Cardoso S, Papagerakis P, Macdougall M, Robert B, Berdal A.
PNAS 2001 Jun; 98(13):7336.
Application:ICC, WB-Tr, Mouse, MO6-G3 cells.
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Endogenous Msx1 antisense transcript: in vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals.
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