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Last updated: 2017/7/23
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ALOX5AP polyclonal antibody

  • Catalog # : PAB6646
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of ALOX5AP.
  • Immunogen:
  • A synthetic peptide corresponding to human ALOX5AP.
  • Sequence:
  • C-KTISTTISPLLLIP
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 18.2
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Western blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • Celecoxib inhibits 5-lipoxygenase.
    Maier TJ, Tausch L, Hoernig M, Coste O, Schmidt R, Angioni C, Metzner J, Groesch S, Pergola C, Steinhilber D, Werz O, Geisslinger G.Biochem Pharmacol. 2008 Oct 1;76(7):862-72. Epub 2008 Jul 19.
  • Applications
  • Western Blot
  • ELISA
  • Application Image
  • Western Blot
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 241
  • Gene Name:
  • ALOX5AP
  • Gene Alias:
  • FLAP
  • Gene Description:
  • arachidonate 5-lipoxygenase-activating protein
  • Gene Summary:
  • This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. [provided by RefSeq
  • Other Designations:
  • MK-886-binding protein,OTTHUMP00000018204,five-lipoxygenase activating protein
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