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UNC13D polyclonal antibody

  • Catalog # : PAB6640
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of UNC13D.
  • Immunogen:
  • A synthetic peptide corresponding to human UNC13D.
  • Sequence:
  • C-KQASQHALRPAP
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 123
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:16000)
    Western blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • UNC13D polyclonal antibody (Cat # PAB6640) (2 ug/mL) staining of human T-lymphocyte lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • UNC13D
  • Gene Alias:
  • FHL3,HLH3,HPLH3,Munc13-4
  • Gene Description:
  • unc-13 homolog D (C. elegans)
  • Gene Summary:
  • This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq
  • Other Designations:
  • unc-13 homolog D
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