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Last updated: 2016/12/4
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PAX3 polyclonal antibody

  • Catalog # : PAB6614
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PAX3.
  • Immunogen:
  • A synthetic peptide corresponding to human PAX3.
  • Sequence:
  • TTLAGAVPRMM-C
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 24.1, 22.7, 53, 53.5
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize all 7 reported human isoforms (as represented by NP_000429.2, NP_0.39230.1, NP_852122,.1 NP_852123.1, NP_852124.1, NP_852125.1 and NP_852126.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Immunohistochemistry (3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • PAX3 polyclonal antibody (Cat # PAB6614) (3 ug/mL) staining of paraffin embedded human esophagus. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5077
  • Protein Accession#:
  • NP_000429.2;NP_0.39230.1;NP_852122;.1NP_852123.1;NP_852124.1;NP_852125.1;NP_852126.1
  • Gene Name:
  • PAX3
  • Gene Alias:
  • CDHS,HUP2,MGC120381,MGC120382,MGC120383,MGC120384,MGC134778,WS1
  • Gene Description:
  • paired box 3
  • Gene Summary:
  • This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq
  • Other Designations:
  • paired box homeotic gene 3,paired domain gene 3,paired domain gene HuP2
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