PITPNM3 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PITPNM3.
Immunogen
A synthetic peptide corresponding to human PITPNM3.
Sequence
C-SWARGPPKFESVP
Host
Goat
Theoretical MW (kDa)
107, 103
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
PITPNM3 polyclonal antibody (Cat # PAB6609, 5 ug/mL) staining of paraffin embedded human cerebral cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PITPNM3
Entrez GeneID
83394Protein Accession#
NP_112497Gene Name
PITPNM3
Gene Alias
CORD5, MGC157740, MGC157741, NIR1, RDGBA3
Gene Description
PITPNM family member 3
Omim ID
608921Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene
Other Designations
PYK2 N-terminal domain-interacting receptor 1|retinal degeneration B alpha 3
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Interactome
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Publication Reference
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Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein.
Lev S, Hernandez J, Martinez R, Chen A, Plowman G, Schlessinger J.
Molecular and Cellular Biology 1999 Mar; 19(3):2278.
Application:IHC, IP, Rat, Brain.
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Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein.
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