AKAP10 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of AKAP10.
Immunogen
A synthetic peptide corresponding to human AKAP10.
Sequence
C-AQYDQPLEKSTKL
Host
Goat
Theoretical MW (kDa)
73.8
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — AKAP10
Entrez GeneID
11216Protein Accession#
NP_009133Gene Name
AKAP10
Gene Alias
D-AKAP2, MGC9414, PRKA10
Gene Description
A kinase (PRKA) anchor protein 10
Gene Ontology
HyperlinkGene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction. [provided by RefSeq
Other Designations
A-kinase anchor protein 10|dual-specificity A-kinase anchoring protein 2|mitochondrial A kinase PPKA anchor protein 10|protein kinase A anchoring protein 10
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Interactome
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Disease
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Publication Reference
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D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain.
Huang LJ, Durick K, Weiner JA, Chun J, Taylor SS.
PNAS 1997 Oct; 94(21):11184.
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D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain.
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