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Last updated: 2016/11/27
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MUTYH polyclonal antibody

  • Catalog # : PAB6606
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of MUTYH.
  • Immunogen:
  • A synthetic peptide corresponding to human MUTYH.
  • Sequence:
  • C-HISTDAHSLNSAAQ
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 60, 59.1, 57.5, 57.4
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize all reported isoforms (NP_0.36354.1, NP_001041636.1, NP_001041637.1, NP_001041638.1, NP_001041639.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • MUTYH polyclonal antibody (Cat # PAB6606) (0.1 ug/mL) staining of human bone marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4595
  • Protein Accession#:
  • NP_0.36354.1;NP_001041636.1;NP_001041637.1;NP_001041638.1;NP_001041639.1
  • Gene Name:
  • MUTYH
  • Gene Alias:
  • MGC4416,MYH
  • Gene Description:
  • mutY homolog (E. coli)
  • Gene Summary:
  • This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • A/G-specific adenine DNA glycosylase,OTTHUMP00000009096,OTTHUMP00000009098,OTTHUMP00000009101,OTTHUMP00000009102,mutY homolog
  • Gene Pathway
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