NOXO1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
NOXO1 polyclonal antibody (Cat # PAB6594) (10 ug/mL) staining of paraffin embedded human kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NOXO1.
Immunogen
A synthetic peptide corresponding to human NOXO1.
Sequence
RGCVDSVPHPTTEQ
Host
Goat
Theoretical MW (kDa)
40.7, 40.8, 41.3
Reactivity
Human
Specificity
This antibody is expected to recognize all three reported isoforms (as represented by NP_653204.1, NP_751907.1and NP_751908.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Immunohistochemistry (10-20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
NOXO1 polyclonal antibody (Cat # PAB6594) (10 ug/mL) staining of paraffin embedded human kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NOXO1
Entrez GeneID
124056Protein Accession#
NP_653204.1;NP_751907.1;NP_751907.1Gene Name
NOXO1
Gene Alias
MGC20258, P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28
Gene Description
NADPH oxidase organizer 1
Omim ID
611256Gene Ontology
HyperlinkGene Summary
NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). NOX organizers, such as NOXO1, target NOX activators (see NOXA1; MIM 611255) to NOX and also target NOX to different subcellular compartments (Opitz et al., 2007 [PubMed 17189823]).[supplied by OMIM
Other Designations
Nox organizer 1|regulatory protein P41NOX
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Publication Reference
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Two novel proteins activate superoxide generation by the NADPH oxidase NOX1.
Banfi B, Clark RA, Steger K, Krause KH.
The Journal of Biological Chemistry 2003 Feb; 278(6):3510.
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Two novel proteins activate superoxide generation by the NADPH oxidase NOX1.
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