PIK3C2A polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
PIK3C2A polyclonal antibody (Cat # PAB6593, 5 ug/mL) staining of paraffin embedded human heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PIK3C2A.
Immunogen
A synthetic peptide corresponding to human PIK3C2A.
Sequence
C-TVKWYQLTAATYL
Host
Goat
Theoretical MW (kDa)
191
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
PIK3C2A polyclonal antibody (Cat # PAB6593, 5 ug/mL) staining of paraffin embedded human heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — PIK3C2A
Entrez GeneID
5286Protein Accession#
NP_002636Gene Name
PIK3C2A
Gene Alias
CPK, DKFZp686L193, MGC142218, PI3-K-C2(ALPHA), PI3-K-C2A
Gene Description
phosphoinositide-3-kinase, class 2, alpha polypeptide
Omim ID
603601Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq
Other Designations
C2-containing phosphatidylinositol kinase|PI3K-C2alpha
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain.
Molz L, Chen YW, Hirano M, Williams LT.
The Journal of Biological Chemistry 1996 Jun; 271(23):13892.
Application：IP, WB-Ce, WB-Tr, Firefly, Monkey, COS-7 cells, Firefly embryos.
-
Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com