XPO7 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of XPO7.
Immunogen
A synthetic peptide corresponding to human XPO7.
Sequence
C-NSTYGVNSNDMMS
Host
Goat
Theoretical MW (kDa)
125, 124
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
XPO7 polyclonal antibody (Cat # PAB6565) staining (0.5 ug/mL) of HeLa lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — XPO7
Entrez GeneID
23039Protein Accession#
NP_055839Gene Name
XPO7
Gene Alias
KIAA0745, RANBP16
Gene Description
exportin 7
Omim ID
606140Gene Ontology
HyperlinkGene Summary
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM
Other Designations
RAN binding protein 16
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Interactome
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Publication Reference
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Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily.
Kutay U, Hartmann E, Treichel N, Calado A, Carmo-Fonseca M, Prehn S, Kraft R, Gorlich D, Bischoff FR.
The Journal of Biological Chemistry 2000 Dec; 275(51):40163.
Application:WB-Ce, Human, HeLa cells.
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Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily.
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